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Growth & Hormonal

The growth-hormone axis and its secretagogues (ipamorelin, CJC-1295, tesamorelin, HGH), the IGF-1 analog LR3, and the neuroendocrine peptides kisspeptin, VIP and Melanotan II.

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Peptide profiles

8 research profiles in Growth & Hormonal, listed alphabetically.

Compound Research area Overview Read the profile
CJC-1295 (no DAC / Mod GRF 1-29) A short-acting GHRH analog — and a clear explanation of DAC vs. no-DAC. CJC-1295 without DAC (Modified GRF 1-29) is a GHRH analog studied for pulsatile growth-hormone release, distinct from the long-acting DAC variant. Read →
HGH (Somatropin) Recombinant human growth hormone — a well-characterized, approved, and tightly regulated hormone. HGH (somatropin) is recombinant human growth hormone, acting via IGF-1 on growth, metabolism, and repair — an approved, prescription-regulated therapeutic. Read →
IGF-1 LR3 An engineered IGF-1 analog that escapes its binding proteins — built as a laboratory reagent, and best understood as one. IGF-1 LR3 (Long R3 IGF-1) is an 83-amino-acid IGF-1 analog with minimal binding-protein affinity, studied in cell-growth, muscle and catabolic-state models and widely used as a cell-culture supplement. Read →
Ipamorelin A highly selective growth hormone secretagogue — with completed Phase 2 human trials. Ipamorelin is a selective pentapeptide GHS-R1a agonist studied for clean growth-hormone release and, in completed Phase 2 trials, for gastrointestinal motility. Read →
Kisspeptin The master neuropeptide that switches on the reproductive hormone axis. Kisspeptin (KP-10) triggers GnRH release to initiate the reproductive axis, with active Phase 3 human research in fertility and reproductive endocrinology. Read →
Melanotan II A non-selective melanocortin agonist whose pharmacology produced two FDA-approved drugs. Melanotan II is a cyclic α-MSH analog acting across melanocortin receptors — the research lineage behind FDA-approved bremelanotide and afamelanotide. Read →
Tesamorelin An FDA-approved GHRH analog that stimulates the body's own growth-hormone release. Tesamorelin is an FDA-approved GHRH analog that raises endogenous growth hormone, with a pivotal Phase 3 record in HIV-associated lipodystrophy. Read →
VIP (Vasoactive Intestinal Peptide) A neuropeptide — studied clinically as aviptadil — with roles in vasodilation, airways, and inflammation. VIP is a 28-amino-acid neuropeptide (clinically, aviptadil) studied for vasodilation, bronchodilation, and immune modulation — reaching Phase 2/3 respiratory trials. Read →

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