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Longevity & Metabolic

Mitochondrial, telomere and metabolic-signaling peptides — NAD+, MOTS-c, Epithalon and the lipotropic blends — and what the longevity and metabolism literature does and does not show.

Peptide profiles

4 research profiles in Longevity & Metabolic, listed alphabetically.

Compound Research area Overview Read the profile
Epithalon (Epitalon) The pineal tetrapeptide with 25 years of geroprotection literature — nearly all of it from a single research school. Epithalon (Epitalon, AEDG) is a synthetic pineal tetrapeptide studied for telomerase activation, melatonin rhythm restoration and lifespan in animal models; most evidence comes from the Khavinson group. Read →
LIPO-C (Lipotropic Injection) A lipotropic MIC + L-carnitine blend — a nutrient combination, not a peptide. LIPO-C is a lipotropic injection of methionine, inositol, choline, and L-carnitine — nutrients used in fat metabolism, not a signaling peptide. Read →
MOTS-c A 16-amino-acid peptide encoded by mitochondrial DNA — the signal that moves to the nucleus under metabolic stress. MOTS-c is a mitochondrial-derived peptide studied for AMPK-mediated metabolic regulation, insulin sensitivity, and exercise physiology; it has reached early human trials. Read →
NAD+ A cellular coenzyme central to energy metabolism and aging — studied in humans via its precursors NMN and NR. NAD+ is a coenzyme central to cellular energy and DNA repair; its precursors NMN and NR are advancing through human metabolic and aging trials. Read →

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