Description
KPV (Lys-Pro-Val) is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (Ξ±-MSH residues 11β13). It retains the parent hormone’s anti-inflammatory signaling without its pigmentation activity, and is studied in inflammatory bowel, skin, and infection models.
Specifications
- Sequence: Lys-Pro-Val (Ξ±-MSH 11β13)
- Molecular formula: C16H30N4O4
- Molecular weight: ~342.4 g/mol
- CAS: 67727-97-3
- Purity: β₯99% (HPLC)
- Form: Lyophilized powder
- Appearance: White to off-white solid
Third-party tested β Tested by Janoshik; see “Additional Information” for the COA.
β οΈ For Laboratory Research Use Only (RUO). This product is intended exclusively for in-vitro laboratory research and is not for human or veterinary use, consumption, diagnostic, or therapeutic purposes. It is not a drug, food, cosmetic, or dietary supplement, and is not intended to diagnose, treat, cure, or prevent any disease. Sale is restricted to qualified research professionals and laboratory institutions. By purchasing, the buyer affirms they are appropriately qualified and will use this product solely for legitimate research.
Areas of Research
- Anti-inflammatory Signaling β studied for inhibition of NF-ΞΊB activation and pro-inflammatory cytokine release in immune and epithelial cells.
- Intestinal Inflammation β examined in colitis and inflammatory-bowel-disease models, including oral and nanoparticle delivery studies.
- Skin & Wound Research β investigated in dermal inflammation, wound-healing, and keratinocyte models.
- Antimicrobial Activity β studied for direct activity against bacterial and fungal pathogens including Candida and S. aureus.
- Mast Cell & Allergic Response β investigated for effects on mast-cell degranulation and allergic inflammation.
Product Care & Storage
- All products are shipped lyophilized, which keeps them stable for shipping for up to 3–4 months. Products must be reconstituted to a liquid by mixing with bacteriostatic water for research and testing.
- Lyophilized / powder form β Store in a cool, dry place away from light; stable at room temperature for several weeks. For long-term storage (months to years), freezing is optimal.
- Reconstituted form β Refrigerate under 39°F; remains stable for up to 30 days.
- Usage β We are unable to provide any dosing instructions; however, all products should be considered pharmaceutical grade.




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